I obviously live in a very different place but the number of abandoned buildings, closed stores and restaurants, and lack of cars tells me these places have seen better days.
If I were to pick a business to be in other than corn and soy farming, it'd have to be a gas station/convenience store. At least have customers.
All that said, the landscape has changed for the spacious. Human-scale objects are less and less common and the sky has taken over as the dominant feature. I told it would happen and it did.